Cell Based Assays
Promega CHK2 Kinase Enzyme System, 1mg
Recombinant full-length human CHK2 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. CHK2 is rapidly phosphorylated and activated in response to replication blocks and DNA damage.
Promega CK1 epsilon Kinase Enzyme System, 10microg
Full-length recombinant human CK1 epsilon was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. CK1 epsilon is a member of the CK1 family of serine/threonine protein kinases, which play an important role in diverse cell processes.
Promega p70S6Kb Kinase Enzyme System, 10microg
Recombinant full-length human p70S6Kb was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. p70S6Kb is a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases and is activated by mitogenic stimuli.
Promega HIPK1 Kinase Enzyme System, 10microg
Recombinant human HIPK1 (156-555) was expressed in Sf9 cells using an N-terminal GST tag. HIPK1 or homeodomain-interacting protein kinase 1 is a ser/thr protein kinase and a member of the HIPK family.
Promega ADP-Glo Kinase Assay + Aurora B Kinase Enzyme System, 1 each
Recombinant full-length human Aurora B was expressed by baculovirus in Sf9 cells using an N-terminal GST tag. Aurora B is a member of the Aurora kinase family that associates with microtubules during chromosome movement and segregation.
Promega ZAP70 Kinase Enzyme System, 1mg
Recombinant full-length human ZAP70 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. ZAP70 is a nonreceptor protein tyrosine kinase (part of the Syk/Zap70 family) that is involved in signaling by the T-cell antigen receptor.
Promega p38 beta Kinase Enzyme System, 10microg
Recombinant full-length human p38 beta was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. p38 beta is a member of the p38 MAP kinase family and is activated by both proinflammatory cytokines and environmental stress.
Promega BMX Kinase Enzyme System, 1mg
Recombinant full-length human BMX was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. The BMX gene encodes a non-receptor tyrosine kinase, which may play a role in the growth and differentiation of hematopoietic cells.
Promega c-KIT Kinase Enzyme System, 10microg
Recombinant human c-KIT (544-end) was expressed by baculovirus in Sf9 insect cells using a N-terminal GST tag. c-KIT is a proto-oncogene and a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor).
Promega LRRK2 Kinase Enzyme System, 10microg
LRRK2 or leucine-rich repeat kinase is a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain and a WD40 domain.
Promega ALK2 Kinase Enzyme System, 10microg
ALK2 is a receptor serine/threonine kinase that is member of the ALK family and is upstream of signaling pathway involving the SMAD proteins especially SMAD1/5/8.
Promega PI3K (p110beta/p85alpha), 20ug, 200microl
The PI3K lipid kinase enzymes are used with ADP-Glo KInase Assay System and Lipid Kinase Substrates in a homogeneous, add-mix-read lipid kinase assay.
Promega ADP-Glo™ Kinase Assay + PKCβI Kinase Enzyme System
Recombinant full-length human PKCβ I was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. PKCβI is a member of the PKC family (phospholipid-dependent serine/threonine kinase) and is highly related to PKCβ II.
Promega EGFR (T790M, L858R) Kinase Enzyme System, 10microg
Recombinant human EGFR (T790M, L858R) (amino acids 695-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. EGFR is receptor for members of the EGF family and a transmembrane glycoprotein that has tyrosine kinase activity.
Promega p38 gamma Kinase Enzyme System, 10microg
Recombinant full-length human p38 gamma was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. p38 gamma is a member of the p38 MAPK family, which is activated in response to stress.